The gap in the long process of progressing a novel scientific
insight into a new medicine is often called “the valley of death”. Read
below to understand how the strategic alliance between University of
Oxford and Novo Nordisk is aiming to combat type 2 diabetes by bridging
this gap
The gap between translating basic research discoveries into medicines
is often called “the valley of death”. The process of progressing a
novel scientific insight into a new medicine is long, challenging,
labour-intensive and expensive and all too often exciting ideas are lost
along the way. The strategic alliance between the University of Oxford and Novo Nordisk aims to bridge that gap, by marrying leading academic science with the
best of pharmaceutical research and development capabilities.
Fuelled by an obesity pandemic,
type 2 diabetes
affects more than 379 million people1 and is today the fastest-growing
chronic disease on a global level2. It is this challenge that research
in the alliance between the University of Oxford and the Novo Nordisk
Research Centre Oxford (NNRCO) aims to address. Since the NNRCO was
announced in January 2017, the stated ambition is to enable scientists
from Novo Nordisk and the University of Oxford to collaborate to
discover innovative approaches for treating type 2 diabetes.
The total investment from Novo Nordisk is expected to be around 1
billion Danish kroner (115 million British pounds) over a period of 10
years3. The centre focuses on the early-stage innovation that often
falls in the “valley” between fundamental insights and clinical
development. It aims to have a substantial impact on the future
treatment of type 2 diabetes and its complications. But what makes the
collaboration unique? The answer lies in bringing the right
translational research insights into a strong collaboration between
academia and industry.
Bringing hope for patients
It is cross-fertilisation between academia and pharma that is the
ultimate goal of the NNRCO, which by many is called ‘a hybrid
institute’. To date, it employs 20 researchers who are already involved
in research projects together with colleagues from Oxford University.
Interim site head of the NNRCO, Allan Ertmann Karlsen says: “I am very
motivated by the activities that we see here at the research centre
every day. Being able to bring excellent fundamental scientists from the
University of Oxford together with experienced researchers and
clinicians from Novo Nordisk to translate their findings into tangible
ideas for further development brings increased hope for patients”
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